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September 24, 2023CureusOpen Access

Cerebrovascular Disease Mortality Trends in Brazil: An In-Depth Joinpoint Analysis

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Key result

Cerebrovascular disease mortality in Brazil falls ~45% between 2000 and 2021.

  • AAPC -2.85
  • 95% CI -2.97 to -2.72
  • P<0.05
  • n=153,748,438

Why the study?

There was a gap in continuous comprehensive studies analyzing evolving cerebrovascular disease mortality rates in Brazil beyond 2019.

Population

People above 20 years of age in Brazil

Comparison

Mortality trends by age, sex, state, and geographic region

Design

Descriptive, ecological, time series study using nationwide data

Follow-up

2000 to 2021

Authors

BMBilly McBenedictWHWilhelmina N HauwangaAEAisha Elamin

Discussion

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Overview

Declining cerebrovascular mortality in Brazil supports sustained prevention monitoring; leaves open identification of key drivers for targeted research.

Study Design

Type

Observational (n=153,748,438)

Structured PICO

P
Population
Over 103 million adults aged 20 and older in Brazil were included in a nationwide ecological time-series study to analyze cerebrovascular disease mortality trends from 2000 to 2021.
O
Outcome
Age-adjusted mortality rates (AAMRs) for cerebrovascular diseasehard clinical

Main Result

Effect estimate: AAPC -2.85 (95% CI -2.97 to -2.72)

Absolute Event Rate: 52% vs 95%

p-value: p=<0.05

Cerebrovascular disease mortality rates in Brazil have significantly decreased across all demographic groups and macro-regions from 2000 to 2021.

Limitations

  • Utilization of secondary data with potential for incorrect ICD code classification of causes of death
  • Possibility of incomplete information leading to loss of data
  • Exclusive emphasis on depicting trends without exploring underlying sociodemographic factors driving these trends

Cite This Study

McBenedict et al. (2023) conducted an observational in Cerebrovascular disease mortality (n=153,748,438). Calendar year (2000-2021) was evaluated on Age-adjusted mortality rate (AAMR) for cerebrovascular disease (AAPC -2.85, 95% CI -2.97 to -2.72, p=<0.05). Between 2000 and 2021, the age-adjusted mortality rate for cerebrovascular disease in Brazil decreased significantly from 95 to 52 deaths per 100,000 inhabitants (AAPC -2.85).

synapsesocial.com/papers/6ab091c4cc4cd448c7ec9380https://doi.org/10.7759/cureus.45845
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