Key result
13C-Hiolein breath test detects steatorrhoea with ~92% sensitivity as an alternative to faecal fat analysis.
Why the study?
The 13C-Hiolein breath test was evaluated as a non-invasive, non-radioactive test for exocrine pancreatic insufficiency with uncertain accuracy and clinical validity compared to standard tests.
Does the 13C-Hiolein breath test accurately detect exocrine pancreatic insufficiency compared to the secretin pancreozymin test and faecal fat analysis?
Observational (n=53)
Does the 13C-Hiolein breath test accurately detect exocrine pancreatic insufficiency compared to the secretin pancreozymin test and faecal fat analysis?
The 13C-Hiolein breath test is a highly sensitive and specific non-invasive alternative to faecal fat analysis for detecting exocrine pancreatic insufficiency.
No takes yet. Share an insight, caveat, or question.
May offer noninvasive alternative to fecal fat analysis for pancreatic steatorrhea; leaves open prospective validation before routine adoption.
Lembcke et al. (1996) conducted an observational in Exocrine pancreatic insufficiency (n=53). 13C-Hiolein breath test vs. Secretin pancreozymin test and faecal fat analysis was evaluated on Sensitivity and specificity for detecting steatorrhoea. The 13C-Hiolein breath test detected steatorrhoea with a sensitivity of 91.7% and a specificity of 85.7%, serving as a convenient alternative to faecal fat analysis.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: