Aziridination of 5-Methyl-4H-1,3-dioxins by N-Tosyliminophenyliodinane: A One-step Procedure for the Synthesis of α-Methylserinal Derivatives

All articles of this category The methyl analogue of Garner's aldehyde, N -tosyl-4-methyl- N , O -isobutyrylideneserinal, has been prepared in a one-step reaction by CuClO 4 -catalyzed aziridination of 2-isopropyl-5-methyl-4 H -1,3-dioxin with N -tosyliminophenyliodinane and transformed into α -methylserine derivatives, e.g. α -vinylalanine. amino aldehydes - aziridination - rearrangements - α -alkyl- α -amino acids - 4 H -1,3-dioxins