Pathological investigation and microbiological confirmation of Bartonella quintana endocarditis: A case of trench fever without the trench or fever

Jason J. LeBlanc; Carl Boodman; L. Robbin Lindsay; Antonia Dibernardo; Courtney Loomer; Heather Coatsworth; Kathryn Bernard; Gregory R. McCracken; Shelly McNeil; Mathieu Castonguay; Glenn Patriquin

doi:10.1016/j.idcr.2025.e02385

January 1, 2025IDCasesOpen Access

Pathological investigation and microbiological confirmation of Bartonella quintana endocarditis: A case of trench fever without the trench or fever

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Key Points

To report the diagnostic confirmation of Bartonella quintana endocarditis in an atypical case presenting without fever or classic clinical indicators.
Reviewed a patient case presenting with infective endocarditis but lacking typical symptoms such as fever.
Performed pathological examinations and targeted microbiological testing using specialized growth media on clinical tissue specimens.
Identified Bartonella quintana as the etiology of culture-negative endocarditis despite low initial clinical and intraoperative suspicion.
Demonstrated that pathological evaluation combined with specialized microbiology laboratory methods successfully uncovers fastidious organisms that evade routine culture.

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Implication

Case report reveals atypical Bartonella quintana endocarditis without classic fever, highlighting the vital role of histopathology and microbiology in culture-negative cardiac infections.

Abstract

endocarditis is recognized as a cause of culture-negative endocarditis, but the diagnosis can be difficult, as symptoms may be non-specific, and the organism requires special conditions (and media) for routine growth. This case emphasizes the value of pathological investigations and microbiology laboratory support in the setting of low clinical and intraoperative suspicion of infective endocarditis.

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LeBlanc et al. (2025) studied this question.

synapsesocial.com/papers/6ab099972de4f15999477aa4 https://doi.org/10.1016/j.idcr.2025.e02385

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Pathological investigation and microbiological confirmation of Bartonella quintana endocarditis: A case of trench fever without the trench or fever

Key Points

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Abstract

Discussion

Cite This Study

Pathological investigation and microbiological confirmation of Bartonella quintana endocarditis: A case of trench fever without the trench or fever

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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