Key result
ASFV infection in pigs causes severe early lymphoid damage and late liver and kidney lesions.
Why the study?
Improving awareness about host–virus interactions in African swine fever virus infection could facilitate understanding of disease pathogenesis and control strategies.
Population
10 ASFV-infected pigs experimentally inoculated with Vietnam's first isolated ASFV
Comparison
Early stage vs late stage of disease based on time of death after onset of viremia
Design
Experimental infection study
Authors
Loading...
Hypothesis-generating for ASFV stage-specific organ pathology; leaves open translation to control strategies.
This study characterizes the host-pathogen interaction in ASFV infection in pigs, showing differential organ damage timing that may inform ASF control strategies.
Oh et al. (2022) studied African swine fever virus (ASFV) infection (n=10). ASFV inoculation vs. Early vs late stage of death was evaluated on Changes in blood parameters, viral loads, and pathological changes. Experimental ASFV infection in 10 pigs caused more severe lymphoid damage in the early stage of disease, while liver and kidney lesions were more severe in the late stage.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: