A branched glycopeptide derivative incorporating two D-mannose 6-phosphate residues was prepared by coupling 6-aminohexyl 6-O-[bis(2,2,2-trichloroethoxy)phosphinyl]-alpha-D-mannopyranoside with N-acetyl-L-tyrosyl-L-aspart-oyldi-L-alanine followed by reductive deprotection of the phosphate group.
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Ichikawa et al. (1990) studied this question.
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