Key result
Pacemaker leads risk bacterial colonization and biofilms due to exposed materials and skin proximity.
Why the study?
Pacemaker infections are a distressing and morbid complication with challenging management due to lead colonization and biofilm formation.
Discusses the challenges of pacemaker lead infections and the rationale for transitioning to leadless pacemakers.
Pacemaker infections are one of the most distressing and morbid complications for patients and can present a challenging management problem for physicians. Pacemaker leads, especially those that dwell in the venous system and inside the cardiac chambers, are prone to becoming colonized with bacteria owing to their sizeable surface area, the nature of their external exposed materials (usually silicone or polyurethane) that are prone to biofilm formation, and their close association with the skin surface at the level of the pacemaker pocket.
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Dulam et al. (2020) conducted a review in Pacemaker infections. Pacemaker leads was evaluated. Pacemaker leads are prone to bacterial colonization and biofilm formation due to their large surface area, exposed materials, and proximity to the skin surface.
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