Key result
Chemotherapy resolves incessant VT driven by an extranodal NK/T-cell lymphoma cardiac metastasis.
Why the study?
Cardiac tumours are rare and can present with symptoms mimicking other cardiac diseases, requiring multimodal imaging and biopsy for diagnosis.
Case Report (n=1)
Cardiac metastasis from extranodal NK/T-cell lymphoma can present as incessant ventricular tachycardia, highlighting the importance of multimodal imaging and biopsy in such rare presentations.
May prompt lymphoma relapse consideration in refractory VT; leaves open optimal diagnostic and therapeutic strategies.
Background: Cardiac tumours are rare but affected patients may present with symptoms mimicking other cardiac diseases. The most frequent symptoms include heart failure, arrhythmias, or embolic phenomena. Case summary: A 39-year-old man with a history of extranodal NK/T-cell lymphoma of the nasal type (ENKTL-NT) in clinical remission presented at our department with incessant ventricular tachycardia. The arrhythmia could only be controlled with a combination of intravenously administered beta-blockers, ajmaline, and amiodarone. Diagnostic workup excluded ischaemia, but imaging revealed a tumour located in the apex of the left ventricle. Endomyocardial biopsy confirmed the diagnosis of cardiac relapse of ENKTL-NT. Upon chemotherapy no further arrhythmias developed. Discussion: Many malignancies can metastasize into the heart. Multimodal imaging including echocardiography, cardiac magnetic resonance imaging, and a positron-emission tomography computed tomography paved the way to the diagnosis that was finally established by endomyocardial biopsy. In the present case, a cardiac metastasis from an ENKTL-NT presented with incessant ventricular tachycardia.
No takes yet. Share an insight, caveat, or question.
Kolesnik et al. (2022) conducted a case report in Cardiac relapse of extranodal NK/T-cell lymphoma presenting with incessant ventricular tachycardia (n=1). Chemotherapy was evaluated on Arrhythmia control. A cardiac metastasis from an extranodal NK/T-cell lymphoma presented with incessant ventricular tachycardia that was successfully controlled upon administration of chemotherapy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: