BACKGROUND: Several reports have suggested an association between prematurity and hepatoblastoma (HB). PROCEDURE: Data were collected by questionnaires from 105 children with HB enrolled in a Children's Cancer Group (CCG) study. RESULTS: Observed over expected rates were increased about 2- and 15+-fold for prematurity (<37 weeks at birth) and low birth weight (<1,000 g) respectively. Similar data were derived from a later CCG study of 36 HB children. CONCLUSIONS: Early reports of a possible association between prematurity and HB have been confirmed.
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Feusner et al. (2002) studied this question.
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