The Selenium and Vitamin E Cancer Prevention Trial (SELECT) by Dr Lippman and 3 colleagues 1 reported that selenium or vitamin E alone or in combination did not prevent prostate 4 cancer.The negative results of this trial confirm the outcomes in the Nutritional Prevention of 5 Cancer (NPC) Trial for those participants with the highest baseline plasma selenium 6 concentration prior to supplementation with selenized yeast. 2 The conclusion from both NPC and 7 SELECT is that daily selenium supplementation will not benefit all persons.Cancer risk 8 reduction with selenium should be expected only in men with low or suboptimal levels prior to 9 supplementation.10 11
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Margaret P. Rayman (2009) studied this question.