Key result
VSD patch closure shows similar LV dyssynchrony to controls, with worse dyssynchrony linked to RBBB.
Why the study?
The long-term effects of an akinetic VSD patch and postoperative RBBB on LV mechanical synchrony and global systolic function in pediatric patients were not studied.
Does the presence of an akinetic VSD patch and postoperative RBBB affect LV mechanical synchrony and global systolic function in pediatric patients late after surgery?
Observational (n=36)
Does the presence of an akinetic VSD patch and postoperative RBBB affect LV mechanical synchrony and global systolic function in pediatric patients late after surgery?
Absolute Event Rate: 2.46% vs 1.75%
p-value: p=.16
Pediatric patients with RBBB late after VSD patch closure exhibit significant LV mechanical dyssynchrony compared to those without RBBB, warranting long-term follow-up despite normal global LV function.
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RBBB after VSD patch closure associates with LV dyssynchrony despite preserved EF; leaves open need for closer monitoring pending larger prospective data.
Reddy et al. (2009) conducted an observational in Ventricular septal defect (VSD) (n=36). VSD patch closure vs. Normal controls was evaluated on Left ventricular intraventricular synchrony (16-segment volumetric dyssynchrony index) (p=.16). VSD patch closure >5 years post-surgery showed similar LV dyssynchrony to controls (2.46% vs 1.75%, P=0.16), but patients with RBBB had significantly worse dyssynchrony than those without (P=0.006).
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