Key result
CKD affects ~6% of South African teachers and is linked to diabetes and higher DBP.
Why the study?
There is a need to determine the feasibility of conducting studies of chronic diseases among large cohorts of African patients and to assess the prevalence of CKD and its association with cardiovascular risk factors among school teachers.
Cross-Sectional (n=489)
CKD is common and clinically silent among relatively young, working individuals in South Africa, and is associated with cardiovascular risk factors like diabetes and higher diastolic blood pressure.
CKD prevalence of ~6% in working South Africans supports targeted screening; leaves open causality and generalizability of diabetes/BP associations.
Background: There is a need to determine the feasibility of conducting studies of chronic diseases among large cohorts of African patients.One aim of the South African feasibility study was to determine the prevalence of chronic kidney disease (CKD) and its association with cardiovascular disease (CVD) risk factors among school teachers.Methods: In a cross-sectional survey of 489 teachers we captured data on demographics, CVD risk factors, anthropometry and blood pressure.Serum glucose, creatinine, cholesterol and urine protein/creatinine ratio was measured.Glomerular filtration rate was estimated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and the Modification of Diet in Renal Disease study equations.Results: The mean (6 standard deviation) age of the participants was 46.3 6 8.5 years, with 70.3% being female and 74.6% of mixed ethnicity.The crude prevalence of CKD using the CKD-EPI equation was 6.1% while the age-adjusted prevalence was 6.4% (95% confidence interval 3.2-9.7%).CKD was associated with the presence of diabetes and higher diastolic blood pressures.Conclusions: In our study population of relatively young, working individuals CKD was common, clinically silent and associated with cardiovascular risk factors.The long-term complications of CKD are serious and expensive to manage and this, therefore, constitutes an important public health problem for South Africa.
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Adeniyi et al. (2016) conducted a cross-sectional in Chronic kidney disease (n=489). Diabetes and higher diastolic blood pressure was evaluated on Age-adjusted prevalence of chronic kidney disease (95% CI 3.2-9.7). The age-adjusted prevalence of chronic kidney disease among school teachers in South Africa was 6.4% (95% CI 3.2-9.7%) and was associated with diabetes and higher diastolic blood pressure.
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