Key result
Staged surgical management of infant tetralogy of Fallot shows ~5% recent mortality versus historical primary repair.
Why the study?
The optimal surgical management strategy for infants with tetralogy of Fallot, especially regarding staged versus primary intracardiac repair, remains uncertain.
Does staged surgical management improve survival in infants with tetralogy of Fallot?
Population
61 consecutive infants 24 months or younger with tetralogy of Fallot
Comparison
Staged surgical management versus primary intracardiac repair
Design
Cohort study over a 12-year period
Follow-up
Through definitive intracardiac repair or death
Authors
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Improved survival after infant TOF shunts in later era may reflect experience gains; leaves open optimal shunt selection today.
Cohort (n=61)
Does staged surgical management improve survival in infants with tetralogy of Fallot?
Absolute Event Rate: 25% vs 14%
Staged surgical management of tetralogy of Fallot in infants with unfavorable anatomy or associated problems yields low recent mortality rates, supporting its continued use in selected patients.
Stephenson et al. (1978) conducted a cohort in Tetralogy of Fallot (n=61). Staged surgical management vs. Primary intracardiac repair (historical) was evaluated on Cumulative mortality. Staged surgical management of tetralogy of Fallot in infants demonstrated a recent cumulative mortality near 5%, compared to a 25% overall cohort mortality and a 14% historical rate for primary repair.