Key result
Orthotopic heart transplantation succeeds in a child with dilated cardiomyopathy and Gitelman syndrome.
Why the study?
Gitelman syndrome is generally benign but has rare associations with arrhythmias and sudden cardiac death, and literature associating GS with cardiomyopathy is scarce.
Case Report (n=1)
Orthotopic heart transplantation can be successfully performed in a pediatric patient with concurrent Gitelman syndrome and dilated cardiomyopathy.
Supports feasibility of heart transplantation in pediatric Gitelman syndrome with cardiomyopathy; single case leaves open need for more evidence.
Gitelman syndrome (GS) is a rare hereditary tubulopathy affecting the distal tubule leading to significant electrolyte disturbances. 1 Although generally a benign condition, rare associations with arrhythmias and sudden cardiac death have been reported. 1 A paucity of literature exists associating GS with cardiomyopathy. We present a child with dilated cardiomyopathy and GS who was successfully treated with orthotopic heart transplantation.
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Solt et al. (2020) conducted a case report in Gitelman syndrome and dilated cardiomyopathy (n=1). Orthotopic heart transplantation was evaluated on Successful treatment. Orthotopic heart transplantation was successfully performed in a child with dilated cardiomyopathy and Gitelman syndrome.
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