Key result
Anatomical analysis reveals coronary sinus defects result from left atrial wall dissolution, not incomplete formation.
Why the study?
The anatomical structure and etiology of interatrial communication through the mouth of the coronary sinus remain incompletely understood and require clarification.
Comparison
Specimens with varying degrees of coronary sinus wall dissolution versus specimens with absent coronary sinus orifice
Design
Observational anatomical study of human embryos and heart specimens
Authors
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Challenges traditional embryologic models of coronary sinus defects; leaves open effects on diagnosis or repair.
Observational (n=16)
Knauth et al. (2002) conducted an observational in Interatrial communication through the mouth of the coronary sinus (n=16). Anatomical examination of the coronary sinus was evaluated on Anatomical findings regarding the development and structure of the coronary sinus defect. Anatomical examination of human embryos and heart specimens revealed that the coronary sinus defect is caused by dissolution of the wall adjacent to the left atrium, not incomplete formation.
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