Key result
Off-pump bypass is associated with similar AKI rates to on-pump surgery but higher post-AKI survival.
Why the study?
Acute kidney injury is a common complication after coronary surgery and perioperative modifiable risk factors for its development need to be defined.
Does off-pump coronary bypass reduce the development of acute kidney injury compared to on-pump coronary bypass in patients undergoing coronary surgery?
Cohort (n=319)
Does off-pump coronary bypass reduce the development of acute kidney injury compared to on-pump coronary bypass in patients undergoing coronary surgery?
Postoperative high blood pressure may be protective against acute kidney injury following coronary bypass surgery, suggesting a potential modifiable target to improve patient outcomes.
SurgeryPostoperatif Kan Basıncı Koroner Baypas Cerrahisi Sonrası Gelişen Akut Böbrek Hasarının Düzenlenebilir Bir Risk Faktörü Olabilir Aim: Acute kidney injury (AKI) is a common complication associated with coronary surgery.This study aims to define perioperative modifiable risk factors for AKI development. Methods:We prospectively observed perioperative parameters, laboratory tests, and outcome variables of 319 consecutive patients.The patients were divided into groups according to onpump or off-pump coronary bypass.Results: The off-pump patients were older (65.15±9.247years vs 60.81±9.659;p=0.001) but he frequency of AKI development was similar between the groups (22% vs 19.9%, p=0.659).Preoperative hypertension, advanced age, high body weight, and prolonged cross-clamp time were associated with postoperative AKI, but postoperative high blood pressure and higher ejection fraction were likely to be protective against AKI development.Expected in-hospital survival in a patient developing AKI after off-pump surgery was better than those with on-pump surgery (88.9% and 84.6%, respectively; p<0.001) Conclusion: Managing postoperative blood pressure according to preoperative level could have the potential to reduce AKI incidence.Keywords: Off-pump coronary artery bypass, acute kidney injury, blood pressure Amaç: Akut böbrek hasarı (ABH) koroner cerrahi sonrası sık görülebilen bir komplikasyondur.Bu çalışma ABH gelişimi ile ilişkili perioperatif değiştirilebilir risk faktörlerini tanımlamayı amaçlamaktadır.Yöntemler: Ardışık 319 hastanın perioperatif parametrelerini, laboratuvar testleri ve sonuç değişkenlerini prospektif olarak gözlemledik.Gruplar pompalı veya pompasız koroner bypass'a göre ayrıldı.Bulgular: Pompasız koroner baypas hastaları daha yaşlıydı (65,15±9,247 ve 60,81±9,659; p=0,001), ancak ABH gelişim sıklığı her iki grupta benzerdi (%22 ve %19,9; p=0,659).Preoperatif hipertansiyon, yaş, yüksek vücut ağırlığı ve kros klemp süresi, postoperatif ABH ile ilişkiliydi, ancak postoperatif yüksek kan basıncı ve yüksek ejeksiyon fraksiyonunun ABH gelişimine karşı koruyucu faktörler olarak belirlendi.Postoperatif dönemde ABH gelişen bir hasta grubunda, pompasız ameliyatı sonrası hastane-sağkalımı, pompa ile baypas ameliyatı yapılanlara göre anlamlı derecede yüksekti (sırasıyla %88,9 ve %84,6; p<0,001).
No takes yet. Share an insight, caveat, or question.
Kahraman et al. (2020) conducted a cohort in Acute kidney injury after coronary bypass surgery (n=319). Off-pump coronary bypass vs. On-pump coronary bypass was evaluated on Acute kidney injury development (p=0.659). Off-pump coronary bypass had similar acute kidney injury rates as on-pump surgery (22% vs 19.9%; p=0.659), but higher in-hospital survival among patients developing AKI (88.9% vs 84.6%; p<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: