In-vitro analysis of the susceptibility of Salmonella typhi to Chloramphenicol and leaf extracts of Cassia occidentalis

In-vitro analysis of the susceptibility of Salmonella typhito Chloramphenicol and leaf extracts of Cassia occidentalis was conducted using ethanol, ether, hot and cold water extracts.Of these leaf extracts, Salmonella typhi was only found to be sensitive to the ether extracts at a concentration of 40, 60, 80, 100, and 120mg/ml with zones of inhibition (mm) of 4.0, 3.0, 5.0, 4.0, and 4.0 respectively.It was however sensitive to two brands of chloramphenicol A and B with zones of inhibition 15.0, 13.0, 14.0, 23.0, and 25.0.20.0, 18.0, 16.0, 21.0 and 20.0 respectively at various concentrations.The result of this study showed that chloramphenicol had higher in vitro activity against Salmonella typhi compared to the leaf extract regardless of the extraction method employed.