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January 1, 2016The AnalystOpen Access

Accurate quantification of apoptosis progression and toxicity using a dielectrophoretic approach

Erin A. Henslee Ruth M. Torcal Serrano Fatima H. Labeed Rita I. Jabr Christopher Fry Michael Hughes Kai F. Hoettges

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Abstract

measurements compared favourably to MTT and were superior to trypan blue, whilst also detecting apoptotic progression faster than Annexin-V.

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Henslee et al. (2016) studied this question.

synapsesocial.com/papers/6ab0d19e4786a3c77bf7f003 https://doi.org/10.1039/c6an01596d

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Detection of apoptosis: A review of conventional and novel techniquesReview · 2010 · 150 citations
2Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophagesOriginal Research · 1992 · 3,321 citations
3Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosisEarly-Phase Clinical Trial · 1994 · 2,068 citations
4A novel assay to measure loss of plasma membrane asymmetry during apoptosis of adherent cells in cultureFeasibility Study · 1996 · 535 citations
5Dielectrophoretic analysis of changes in cytoplasmic ion levels due to ion channel blocker action reveals underlying differences between drug-sensitive and multidrug-resistant leukaemic cellsOriginal Research · 2007 · 52 citations

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