Key result
Multimodality imaging and multidisciplinary treatment guide management of rare primary cardiac intimal pleomorphic sarcomas.
Case Report (n=2)
No
Highlights the diverse and severe clinical presentations of primary cardiac intimal pleomorphic sarcoma, including heart failure and ischemic stroke with subsequent metastasis.
Rare cardiac sarcoma presentations with HF or stroke warrant consideration in atypical cases; leaves open optimal diagnostic strategies and management.
We report two patients with primary cardiac sarcomas. The first patient was admitted for dyspnea on exertion secondary to congestive heart failure. She was later diagnosed with intimal pleomorphic sarcoma involving the right ventricular outflow tract extending into the pulmonary artery, which was further complicated by metastasis to the lung. The second patient was admitted for left-sided weakness secondary to a right frontal lobe ischemic stroke. The patient was later diagnosed with left atrial intimal pleomorphic sarcoma, which was further complicated by metastasis to the small bowel and right femur.
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Alam et al. (2020) conducted a case report in Primary cardiac undifferentiated high-grade intimal pleomorphic sarcoma (n=2). Surgical resection and adjuvant therapy (immunotherapy, chemotherapy, radiotherapy) was evaluated on Clinical outcome.
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