Key result
Asymptomatic Carotid Surgery Trial patients present with 80% median ipsilateral stenosis and frequent echolucent plaque.
Why the study?
It was uncertain whether ACST centres have entered and can identify high risk patients using duplex ultrasound for carotid stenosis assessment.
Observational (n=1,657)
Yes
The Asymptomatic Carotid Surgery Trial (ACST) is successfully recruiting high-risk patients using experienced operators and high-quality duplex ultrasound equipment, despite some methodological variations across centers.
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Confirms ACST enrolled appropriate high-risk patients; supports trial validity but leaves applicability to contemporary cohorts open.
Robless et al. (1998) conducted an observational in Asymptomatic carotid stenosis (n=1,657). Duplex ultrasound evaluation was evaluated on Baseline carotid stenosis and plaque characteristics. Among 1,657 patients randomized in the Asymptomatic Carotid Surgery Trial, median ipsilateral stenosis was 80% and one-third had ipsilateral echolucent plaque.
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