Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 18, 2016European Journal of Cardio-Thoracic SurgeryOpen Access

Redo procedures for degenerated stentless aortic xenografts and the role of valve-in-valve transcatheter techniques†

View Full Paper
Ask AI
Bookmark
Share

Key result

Valve-in-valve TAVI yields similar 1-year survival to redo surgery for degenerated stentless aortic valves.

  • P=0.76
  • n=52

Why the study?

Reinterventions for degenerated stentless aortic xenografts are challenging and the role of valve-in-valve transcatheter techniques compared to redo surgery requires evaluation.

Does valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) improve outcomes compared to reoperation in patients with degenerated stentless aortic xenografts?

Population

52 consecutive patients undergoing reintervention for failed stentless aortic valves

Comparison

Valve-in-valve transcatheter aortic valve implantation vs redo surgery

Design

Cohort study

Follow-up

1 year

Authors

HGHerko GrubitzschSZSebastian ZobelTCTorsten Christ

Discussion

Loading...

Member takes

Overview

ViV-TAVI suits selected high-risk patients but carries notable complications; leaves open standardized selection criteria for reintervention.

Study Design

Type

Cohort (n=52)

Structured PICO

Does valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) improve outcomes compared to reoperation in patients with degenerated stentless aortic xenografts?

P
Population
52 patients (mean age 72.3 years) undergoing reintervention for failed stentless aortic valves, assigned to redo surgery or ViV-TAVI, with 1-year follow-up.
E
Exposure
Valve-in-valve transcatheter aortic valve implantation (ViV-TAVI)
C
Comparator
Reoperation (redo surgery)
O
Outcome
1-year survivalhard clinical

Main Result

Absolute Event Rate: 81.5% vs 83.1%

p-value: p=0.76

ViV-TAVI is a viable alternative to redo surgery for degenerated stentless aortic valves, offering similar 1-year survival but carrying specific procedural risks such as coronary obstruction.

Cite This Study

Grubitzsch et al. (2016) conducted a cohort in Degenerated stentless aortic xenografts (n=52). Valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) vs. Redo surgery was evaluated on 1-year survival (p=0.76). Valve-in-valve TAVI resulted in similar 1-year survival compared to redo surgery for degenerated stentless aortic valves (81.5% vs 83.1%, P=0.76).

synapsesocial.com/papers/6ab0d910e30461dadc64b93fhttps://doi.org/10.1093/ejcts/ezw397
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prospectively Randomized Evaluation of Stentless Versus Conventional Biological Aortic Valves : Impact on Early Regression of Left Ventricular Hypertrophy1999 · 139 citations
  2. 2Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document†2012 · 1,054 citations
  3. 3Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document (VARC-2)2012 · 3,374 citations
  4. 4Transcatheter Aortic Valve Implantation in Degenerate Failing Aortic Homograft Root Replacements2011 · 21 citations