Key result
Adrenaline pre-treatment increases brown adipose tissue contrast enhancement by ~48% vs controls in rats.
Why the study?
A non-invasive method to study modifications in lipid depots induced by hormonal stimulation could extend knowledge of adipose tissues.
Population
Rats with interscapular brown adipose tissue
Comparison
Adrenaline pre-treatment vs control
Design
Contrast-enhanced MRI study
Authors
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Supports preclinical BAT imaging optimization; leaves open clinical translation and human validation.
Absolute Event Rate: 83% vs 56%
p-value: p=< 0.05
Sbarbati et al. (2006) studied this question. Adrenaline vs. Controls was evaluated on Enhancement of interscapular brown adipose tissue (IBAT) (p=< 0.05). Adrenaline pre-treatment significantly increased contrast enhancement of interscapular brown adipose tissue in rats compared to controls (83% vs 56%, P < 0.05).
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