Key result
Diet-induced thermogenesis shows no association with stimulated brown adipose tissue activity in healthy men.
Why the study?
The relationship between diet-induced thermogenesis and brown adipose tissue activity in healthy men was unclear.
Is diet-induced thermogenesis related to brown adipose tissue activity in healthy men?
Is diet-induced thermogenesis related to brown adipose tissue activity in healthy men?
Diet-induced thermogenesis in humans is likely not mediated by brown adipose tissue, unlike cold-induced thermogenesis.
Supports dissociation of diet-induced thermogenesis from brown adipose tissue; hypothesis-generating and requires prospective confirmation before clinical consideration.
Cold-induced thermogenesis (CIT) was related to BAT activity as determined by FDG-PET/MRI after stimulation of BAT. Diet-induced thermogenesis (DIT) was not related to stimulated BAT activity. Supraclavicular skin temperature was related to CIT but not to DIT. DIT in humans is probably not a function of BAT.
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Loeliger et al. (2020) studied this question. Diet-induced thermogenesis is not related to stimulated brown adipose tissue activity in healthy men, indicating that it is probably not a function of brown adipose tissue.
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