We prove that the HOMFLYPT polynomial of a link colored by partitions with a fixed number of rows is a q-holonomic function. By specializing to the case of knots colored by a partition with a single row, it proves the existence of an (a,q) superpolynomial of knots in 3-space, as was conjectured by string theorists. Our proof uses skew-Howe duality that reduces the evaluation of web diagrams and their ladders to a Poincaré–Birkhoff–Witt computation of an auxiliary quantum group of rank the number of strings of the ladder diagram. The result is a concrete and algorithmic web evaluation algorithm that is manifestly q-holonomic.
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