Primary Squamous Cell Carcinoma of the Endometrium : A Rare Case in the Philippines

Introduction: Primary Squamous Cell Carcinoma of the Endometrium (PSCCE) is an extremely rare case accounting for only 0.1% of all endometrial cancer cases. It usually occurs in post-menopausal women. Case: We reported a case in the Philippines, a 64-year-old, multiparous, post-menopausal woman who presented with post-menopausal bleeding. Procedure: Endometrial curettage showed squamous cell carcinoma. She then underwent Exploratory Laparotomy, Radical Hysterectomy with Bilateral Salpingo-oophorectomy, with Bilateral Pelvic Lymph Node Dissectionand Peritoneal Fluid Cytology. Results: Histopathology of the uterus showed squamous cell carcinoma, keratinizing, with full thickness myometrial invasion. Postoperative diagnosis was primary squamous cell carcinoma, keratinizing, endometrium, stage IIIA. Patient was advised to undergo chemotherapy and radiotherapy. Conclusion: The etiology of PSCCE is still unclear and usually presents with vaginal bleeding in post-menopausal women. To diagnose, histology should meet three criteria asdefined by Fluhmann. The prognosis is poor and related to stage at diagnosis.