Key result
Individualized ramp protocols yield similar exercise capacity to step protocols in elderly patients.
Why the study?
It was unclear whether individualized ramp protocols provide better peak cardiopulmonary responses and VO2 prediction accuracy than step protocols in patients aged 60 years or older referred for exercise testing.
Does an individualized ramp protocol improve peak cardiopulmonary responses and VO2 prediction accuracy compared to a step protocol in patients ≥60 years with known or suspected CAD?
RCT (n=24)
Random order
Does an individualized ramp protocol improve peak cardiopulmonary responses and VO2 prediction accuracy compared to a step protocol in patients ≥60 years with known or suspected CAD?
Individualized ramp and step protocols yield similar peak cardiopulmonary responses and VO2 estimates in elderly patients when selected based on pretest activity.
Answers are grounded in this paper and cite their sources.
Similar cardiopulmonary responses and VO2 estimates occur with matched ramp or step protocols in older CAD patients; leaves open advantages in broader or outcome-focused settings.
To evaluate whether individualized ramp protocols may be better than step protocols in patients > or = 60 years of age referred for exercise testing, peak cardiopulmonary responses and accuracy in prediction of oxygen uptake (VO2) for individualized ramp and step protocols (Bruce or modified Bruce) were compared. Twenty-four subjects (67+/-3 years) with known or suspected coronary artery disease performed both tests in random order. Protocols were selected based on estimated exercise capacity using a pretest activity questionnaire. No differences were observed between peak VO2 (19.3+/-6.3 and 19.1+/-6.4 ml/kg/min), heart rate (127+/-15 and 126+/-16 beats/min), rate-pressure product (24.0+/-4.8 and 23.4+/-4.9 beats/min x mm Hg x 10(3)) and anaerobic threshold (16.6+/-3.7 and 16.0+/-4.7 ml/kg/min) for the ramp and step protocols, respectively. The relation between measured submaximal VO2 and American College of Sports Medicine (ACSM)-predicted VO2 during the ramp protocol is demonstrated by the regression coefficient (beta), where beta = 0.92 (95% confidence intervals [CI] 0.85 to 0.99) and for the step protocols where beta = 1.02 (95% CI 0.84 to 1.20). Peak cardiopulmonary responses in the elderly are similar during individualized ramp and step protocols when appropriately selected based on a pretest activity questionnaire. Both protocols appear to provide clinically reasonable estimates of VO2 when gas exchange analysis is not used.
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Bader et al. (1999) conducted an RCT in Known or suspected coronary artery disease (n=24). Individualized ramp protocols vs. Step protocols (Bruce or modified Bruce) was evaluated on Peak oxygen uptake (VO2). Individualized ramp protocols yielded similar peak cardiopulmonary responses compared to step protocols in elderly patients, with exercise capacity of.
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