Funding sources: None. Conflicts of interest: None declared. Madam, A 3‐year‐old girl visited Kanazawa University Hospital with a history of skin lesions on her face lasting several months. At the time of her first visit in March 2007, she had umbilicated vesiculopapules with small necrotic centres and erythematous oedema on her face (Fig. 1a) and upper limbs, as well as aphthous stomatitis. The skin lesions were exacerbated by sun exposure. She also had a low‐grade fever and general malaise. Blood cell and platelet counts were normal. No atypical lymphocytes were found in peripheral blood smears. Computed tomography did not detect any abnormity. Anti‐Epstein–Barr virus (EBV) antibody titres indicated a previous infection pattern of EBV, but a high amount of EBV DNA (4·4 × 105 copies per 106 white blood cells) was detected in peripheral blood mononuclear cells (PBMC). Informed consent was obtained according to the Declaration of Helsinki, and approval for the study was obtained from the Human Research Committee of Kanazawa University.
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Tanaka et al. (2011) studied this question.