Key result
Non-Newtonian blood models alter simulated wall shear stress profiles in arterial stenosis and aneurysms.
Why the study?
Mathematical modeling of blood flow in arteries requires comparison of Newtonian and non-Newtonian models to assess their effects on pulsatile blood flow simulations.
This computational study investigates the differences between Newtonian and non-Newtonian blood flow models in simulating pulsatile flow through arterial stenosis and aneurysm models.
Non-Newtonian effects may alter simulated hemodynamics in stenosis and aneurysms; leaves open optimal model selection for clinical translation.
Mathematical modeling of blood flows in the arteries is an important and challenging problem. This study compares several non-Newtonian blood models with the Newtonian model in simulating pulsatile blood flow through two three-dimensional models of an arterial stenosis and an aneurysm. Four non-Newtonian blood models, namely the Power Law, the Casson, the Carreau, and the Generalized Power Law, as well as the Newtonian model of blood viscosity, are used to investigate the flow effects induced by these different blood constitutive equations. The aim of this study is three-fold: firstly, to investigate the variation in wall shear stress in an artery with a stenosis or aneurysm at different flow rates and degrees of severity; secondly, to compare the various blood models and hence quantify the differences between the models and judge their significance; and lastly, to determine whether the use of the Newtonian blood model is appropriate over a wide range of shear rates.
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Husain et al. (2013) studied Arterial stenosis and aneurysm. Non-Newtonian blood models (Power Law, Casson, Carreau, Generalized Power Law) vs. Newtonian model of blood viscosity was evaluated on Variation in wall shear stress at different flow rates and degrees of severity. Non-Newtonian blood models were compared with the Newtonian model to investigate wall shear stress variations in simulated arterial stenosis and aneurysms.
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