Key result
En bloc RCC resection with xeno-pericardial patch IVC repair shows 0% mortality and severe morbidity.
Why the study?
Surgical approaches for tumor thrombus in the inferior vena cava complicated with kidney cancer require evaluation to achieve en bloc resection with minimal organ damage.
Is en bloc resection with xeno-pericardial patch repair of the IVC safe and effective for patients with renal cell carcinoma and IVC tumor thrombus?
Observational (n=12)
Is en bloc resection with xeno-pericardial patch repair of the IVC safe and effective for patients with renal cell carcinoma and IVC tumor thrombus?
En bloc resection with xeno-pericardial patch repair of the IVC is a feasible and safe approach for managing IVC tumor thrombus in renal cell carcinoma.
Supports feasibility of xeno-pericardial patch repair for RCC with IVC thrombus; leaves open need for comparative trials.
BACKGROUND AND OBJECTIVES: For tumor thrombus in the inferior vena cava (IVC) complicated with kidney cancer, we built a surgical team to achieve (1) en bloc tumor resection; (2) xeno-pericardial patch IVC repair; and (3) minimum organ damages. We reviewed outcome of the case series to verify rationale of this approach. METHODS: A consecutive series of 12 patients having the IVC tumor thrombus by renal cell carcinoma in the last 3 years was enrolled. Minimum kidney ischemia was induced in five cases (Procedure I), whereas liver and kidney ischemia was induced in five cases (Procedure II). Mild hypothermic extracorporeal circulation was used in two cases (Procedure III). RESULTS: There was no mortality or severe morbidities related to the surgery. Postoperative recovery was most prompt by the Procedure I. Liver and kidney ischemic time was longer in the Procedure III than the Procedure II, whereas organ function was not substantially impaired in either series. The resected IVC margin was free from the cancer in all cases, while local recurrence was not seen in any cases. CONCLUSIONS: En bloc resection with xeno-pericardial patch repair of the IVC was successfully performed in the tumor thrombus complicated with kidney cancer with minimum organ damage.
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Fukushima et al. (2017) conducted an observational in Renal cell carcinoma with inferior vena cava tumor thrombus (n=12). En bloc tumor resection with xeno-pericardial patch IVC repair was evaluated on Mortality or severe morbidities related to the surgery. En bloc resection with xeno-pericardial patch repair of the inferior vena cava for renal cell carcinoma tumor thrombus resulted in 0% mortality, severe morbidity, and local recurrence.
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