Key result
Paclitaxel-coated balloons for main vessel lesions are linked to ~0.6 mm2 larger side-branch ostial areas.
Why the study?
The effects on the side-branch ostium following paclitaxel-coated balloon treatment of de novo coronary lesions of main vessels have not been previously investigated.
Does paclitaxel-coated balloon treatment of de novo coronary lesions of main vessels improve side-branch ostial lumen area in patients with side-branches ≥1.5 mm?
Comparison
Pre-procedure vs post-procedure vs 9-month follow-up after PCB treatment
Design
Prospective single-center observational study
Follow-up
9 months
Authors
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SB ostial lumen gain after main-vessel PCB was associated with late enlargement; hypothesis-generating for bifurcations and needs randomized confirmation.
Observational (n=16)
No
Does paclitaxel-coated balloon treatment of de novo coronary lesions of main vessels improve side-branch ostial lumen area in patients with side-branches ≥1.5 mm?
Mean Difference: 0.6
Absolute Event Rate: 1.42% vs 0.92%
p-value: p=0.028
Paclitaxel-coated balloon treatment of de novo main vessel coronary lesions is associated with an increase in side-branch ostial lumen area at 9 months, suggesting favorable remodeling.
Her et al. (2016) conducted an observational in De novo coronary lesions of main vessels (n=16). Paclitaxel-coated balloon was evaluated on Side-branch ostial lumen area (MD 0.60 mm2, p=0.028). Paclitaxel-coated balloon treatment of de novo coronary lesions of main vessels significantly increased the side-branch ostial lumen area by a mean of 0.60 mm2 at 9-months follow-up.
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