Key result
Silent ischemia affects 28% of asymptomatic T2D patients, linked to elevated HbA1c and dyslipidemia.
Why the study?
Diabetes causes autonomic neuropathy that can blunt pain alert mechanisms, contributing to a higher incidence of painless myocardial infarctions in diabetes.
What is the prevalence of silent coronary artery disease detected by stress test in patients with type 2 diabetes, and what are the associated risk factors?
Cross-Sectional (n=100)
No
What is the prevalence of silent coronary artery disease detected by stress test in patients with type 2 diabetes, and what are the associated risk factors?
In patients with type 2 diabetes, elevated HbA1c, dyslipidemia, and high blood glucose are significantly associated with silent myocardial ischemia detected by stress testing.
May support neuropathy-linked silent MI screening in diabetes; leaves open need for prospective validation before practice change.
Background: Coronary heart disease is the common impact of death worldwide in DM and 10 % of the population attributable risk of a first MI.4In today's world, most of the deaths are attributable to noncommunicable disease and just over half of these are as a result of IHD.In India, the situation is no different from other part of the world.Diabetes can cause autonomic neuropathy which can blunt any pain alert mechanism contributing towards higher incidence of painless myocardial infarctions in diabetes.Methods: 100 patients with Diabetes Mellitus according to American Diabetes Association criteria, who are willing to participate in our study age more 20 years and less than 80 years attending OPD or admitted in Department of General Medicine Dr. D. Y. Patil medical college, hospital and research centre, pimpri, pune during the study period from May 2017 to April 2020.Results: Out of 100 cases 53 were males 47 were females the positive stress test for ishemic heart disease was observed in 28 patients out of them 14 were males and 14 were females.there was statistically significance (p<0.05) in mean values of BSL(F&PP1), HbA1C, total cholesterol, triglyceride and LDL for stress test positive and negative groups.Conclusions: Increase in HbA1c levels, dyslipidaemia and elevated blood glucose levels were associated significantly with incidence of silent MI in patients with type 2 diabetes.It is recommended that control of sugars is necessary for prevention of coronary artery disease.
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Dr Nuvvula Siva Krishna (2019) conducted a cross-sectional in Type 2 Diabetes Mellitus (n=100). Treadmill Stress Test (TMT) was evaluated on Positive treadmill stress test (silent myocardial ischemia). Among asymptomatic patients with type 2 diabetes, 28% had a positive treadmill stress test for silent myocardial ischemia, which was significantly associated with elevated HbA1c and dyslipidemia.
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