Key result
PAD is linked to ~65% prevalence of coexistent CAD alongside high rates of medical therapy.
Why the study?
Clinical characteristics, risk factors, and medical treatment patterns of patients with peripheral arterial disease followed in an academic vascular surgery clinic were not fully described.
Observational (n=561)
No
Patients with PAD managed in an academic vascular surgery clinic have a high prevalence of CAD and cardiovascular risk factors, but also receive high rates of appropriate medical therapies.
The charts of all 561 patients (69% men and 31% women, mean age 71 +/- 10 years) with peripheral arterial disease (PAD) followed in an academic vascular surgery clinic were reviewed. Coexistent coronary artery disease (CAD) was present in 364 of 561 patients (65%). Of the 561 patients with PAD, 442 (79%) were current or exsmokers, 385 (69%) had hypertension, 225 (40%) had diabetes, 358 (64%) had a serum low-density lipoprotein (LDL) cholesterol > or =100 mg/dL, and 228 (41%) had a serum high-density lipoprotein cholesterol <40 mg/dL. Cilostazol or pentoxifylline was given to 301 of 301 patients (100%) with intermittent claudication. Aspirin or clopidogrel was given to 501 of 561 patients (89%) with PAD. Statins were given to 282 of 358 patients (79%) with PAD and an increased serum LDL cholesterol. If CAD was present, beta blockers were given to 301 of 364 patients (83%) and angiotensin-converting enzyme inhibitors or angiotensin receptor blockers to 303 of 364 patients (83%).
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Sukhija et al. (2005) conducted an observational in Peripheral arterial disease (PAD) (n=561). Peripheral arterial disease was evaluated. Peripheral arterial disease in 561 patients was associated with a 65% prevalence of coexistent coronary artery disease and high rates of appropriate medical therapy, including 89% on antiplatelets.
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