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The reaction of allenic nitriles with 2-aminobenzimidazoles gives 2-aminopyrimido[1,2-a]benzimidazoles 5 in very good yields. The pharmacological screening of compound 5a, 5d and 5i shows that they possess slight antibiotic and antiarrythmic properties.
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Asobo et al. (2001) studied this question.
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