Key result
Degos' disease linked to biventricular constrictive dysfunction without coronary stenosis or impaired flow reserve.
Why the study?
The relationship between Degos' disease and constrictive pericarditis causing left ventricular wall motion abnormality was investigated.
Case Report (n=1)
This case suggests that Degos' disease can cause constrictive pericarditis and left ventricular wall motion abnormalities, likely due to pericardial vasculitis.
Degos' disease may cause constrictive pericarditis; this single case leaves open its prevalence and need for cardiac screening.
A 47-year-old man with Degos' disease was examined by echocardiography, which showed hypokinesis of the apical left ventricular wall with pericardial effusion. To evaluate the myocardial perfusion and coronary flow reserve, 201Tl scintigraphy and intracoronary Doppler flowmetry were performed. The coronary flow reserve was not decreased nor was there angiographical coronary stenosis, although a pressure study revealed constrictive dysfunction of both ventricles. The constrictive pericarditis might have been induced by pericardial vasculitis, thereby causing the left ventricular wall motion abnormality.
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Yukiiri et al. (2000) conducted a case report in Degos' disease with constrictive pericarditis (n=1). Diagnostic evaluation (echocardiography, scintigraphy, Doppler flowmetry, pressure study) was evaluated on Constrictive dysfunction and myocardial perfusion. In a 47-year-old man with Degos' disease, a pressure study revealed constrictive dysfunction of both ventricles without decreased coronary flow reserve or angiographical coronary stenosis.
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