What question did this study set out to answer?

To identify predictors of between- and within-patient changes in health status across the first 12 months following left ventricular assist device (LVAD) implantation.

March 11, 2014European Journal of Heart FailureOpen Access

Predictors of Changes in Health Status Between and Within Patients 12 Months Post Left Ventricular Assist Device Implantation

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Authors

CBCorline BrouwersZorginstituut Nederland NJNicolaas de JongeUtrecht University KÇKadir ÇalişkanErasmus MC

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Implication

Longitudinal study reveals early health status gains post-LVAD in heart failure patients, suggesting psychological factors strongly shape long-term recovery variations.

Key Points

To identify predictors of between- and within-patient changes in health status across the first 12 months following left ventricular assist device (LVAD) implantation.
Longitudinal assessment of 54 LVAD recipients (74% men, mean age 54 ± 9 years).
Evaluated health status using the Kansas City Cardiomyopathy Questionnaire (KCCQ) and Short-Form 12 (SF-12) at 3–4 weeks post-implant (baseline), and at 3, 6, and 12 months follow-up.
Health status improved significantly from baseline to 3 months across KCCQ clinical summary (F = 33.49, P < 0.001), KCCQ overall summary (F = 31.13, P < 0.001), SF-12 physical component (F = 31.59, P < 0.001), and SF-12 mental component scores (F = 21.77, P < 0.001), with no significant changes between 3 and 12 months (all P > 0.05).
Higher anxiety and depression over time, older age, lower ejection fraction, and greater comorbidity independently predicted poorer health status trajectories on KCCQ and SF-12 subscales.
Sociodemographic, clinical, and psychological factors explained 82.6% of between-patient variance in mental component summary scores, but only 41.9% of KCCQ overall, 36.2% of KCCQ clinical, and 23.2% of physical component summary scores.

Cite This Study

Brouwers et al. (2014) studied this question.

synapsesocial.com/papers/6ab1eba00d6d04de1a8fc2c8 https://doi.org/10.1002/ejhf.75

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Implication

Longitudinal study reveals early health status gains post-LVAD in heart failure patients, suggesting psychological factors strongly shape long-term recovery variations.

Predictors of Changes in Health Status Between and Within Patients 12 Months Post Left Ventricular Assist Device Implantation

Discussion

Member takes

Implication

Key Points

Cite This Study

Predictors of Changes in Health Status Between and Within Patients 12 Months Post Left Ventricular Assist Device Implantation

Discussion

Member takes

Implication

Key Points

Cite This Study

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