Key result
Pre- and post-procedural anemia predict ~82% higher AKI risk and increased mortality following TAVI.
Why the study?
The relationship between anemia, renal insufficiency, and outcomes in patients undergoing TAVI has not been thoroughly studied.
Does pre- and post-procedural anemia increase the incidence of acute kidney injury and 1-year mortality in patients undergoing TAVI?
Population
3,472 patients undergoing TAVI from the French national TAVI registry
Comparison
Pre- and post-procedural anemia severity groups vs no/mild anemia and lower hemoglobin drop groups
Design
Cohort study
Follow-up
1 year
Authors
Loading...
Pre- and post-procedural anemia were associated with higher AKI and 1-year mortality after TAVI; leaves open whether correction modifies risk.
Cohort (n=3,472)
Yes
Does pre- and post-procedural anemia increase the incidence of acute kidney injury and 1-year mortality in patients undergoing TAVI?
Odds Ratio: 1.82
Absolute Event Rate: 10% vs 5%
p-value: p=<0.01
Pre- and post-procedural anemia are significant predictors of acute kidney injury and 1-year mortality in patients undergoing TAVI.
Arai et al. (2015) conducted a cohort in Transcatheter aortic valve implantation (TAVI) (n=3,472). Pre- and post-procedural anemia vs. No or mild anemia was evaluated on Acute kidney injury (OR 1.82, p=<0.01). Pre- and post-procedural anemia were significant predictors of acute kidney injury (OR 1.82, P<0.01) and 1-year mortality (HR 1.44 and HR 1.50, respectively, P<0.01) following TAVI.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: