Key result
Modest elevations in serum creatinine and urinary albumin excretion are associated with increased cardiovascular disease risk in both high-risk and general populations.
Microalbuminuria and modest elevations in serum creatinine are associated with increased CVD risk, highlighting the importance of screening for renal disease in patients with CVD risk factors.
Cardiovascular disease (CVD) is the commonest cause of death in patients with end-stage renal disease (ESRD). Moreover, higher rates of CVD are seen in patients with moderate and even mild renal dysfunction [1]. Recent studies have indicated [2,3] that even modest elevations in serum creatinine and urinary albumin excretion are associated with increased CVD risk, not only in subjects with diabetes or hypertension but also in the general population. It is important to screen for renal disease in those with hypertension, diabetes, and other CVD risk factors because it predicts those who are at high risk for major CVD events.
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Hisashi Adachi (2014) conducted a review in Cardiovascular disease and renal dysfunction. Microalbuminuria and elevated serum creatinine was evaluated on Cardiovascular disease risk. Modest elevations in serum creatinine and urinary albumin excretion are associated with increased cardiovascular disease risk in both high-risk and general populations.
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