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This research analyzed the relationship between mobile device dependence and internalizing problems in Ecuadorian university students, identifying differences based on gender, time spent using cell phones, and demographic characteristics. A quantitative, analytical, descriptive, explanatory, and cross-sectional study was conducted. The study sample consisted of 3,203 university students based on a non-probability sample. 37.7% were men, and 64.3% were women, with a mean age of 21.50 years. The TDM cell phone dependence test and the GADS anxiety and depression scale were administered. The study found that cell phone dependence among university students is moderate, manifesting through symptoms such as withdrawal, tolerance, and impulse control difficulties. A strong correlation was observed between problematic cell phone use and an increase in anxiety and depression. Furthermore, mobile dependence had a significant impact on internalizing disorders, and differences were identified based on gender and time of cell phone use. Implementing programs that prevent, and curb problematic mobile phone use is recommended.
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