Commentary to: Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: the mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1# Xin-zhi Huang, Jie Wang, Chao Huang, Yu-ying Chen, Gui-ying Shi, Qing-shen Hu, Jing Yi
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Yi Sun (2008) studied this question.