o-Nitrophenols and o-nitroaniline were reacted with amines at 210-215°C to produce the corresponding benzoxazoles and benzimidazoles, respectively, in moderate yields. The reactions between o-nitrophenols containing a CO 2 Me or OMe group on their benzene rings and N,N-diethylaniline were examined to investigate the effects of the position and electronic character of these substituents on the formation of the oxazole ring.
No takes yet. Share an insight, caveat, or question.
Nishioka et al. (2004) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: