coverage of the screening program.One explanation is the ever increasing use of imaging techniques as "opportunistic" clinical tools.7 The present data show the large increase in the incidence of breast cancer in the screened population of women.A proportion of the increase is undoubtedly due to changing risk factors related to fertility and child bearing (early menarche, late first pregnancy, low parity), but the main part is likely to be due to mammographic screening, used by a majority of the target population of women.Even though there is no noticeable decrease in incidence at older age, which would be predicted by an effective screening, there is no increase either.As such, these types of ecological data do not allow conclusions about the benefits of screening, particularly, because we do not know how the incidence would have changed without screening.However, a drastic remodeling of the age-incidence relationship in breast cancer has taken place, and the change is likely to continue.Undoubtedly, opportunistic screening will have similar effects, which will be noted in all developed countries when the proportion of screened women will increase.Breast cancer will definitely become a disease of middleaged women.
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Breccia et al. (2004) studied this question.
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