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3-Azabicyclo [3. 3. 1] nonane derivatives were prepared and tested biologically. Some of these, 3-methyl-9β-alkoxy-9α-phenyl-3-azabicyclo [3. 3. 1] nonane (6-8) and their 3- (β-phenylethyl-) analogs (18-20) exhibited promising analgesic activities. Furthermore, 3-methyl-9-benzoyloxy-3-azabicyclo [3. 3. 1] nonane (24 and 25) displayed a marked local anaesthetic action.
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Ohki et al. (1970) studied this question.
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