Key result
Acute coronary syndrome is linked to ~44% lower CAC scores than chronic CAD.
Why the study?
The clinical significance of coronary artery calcification and its relationship with different types of ischemic heart disease and risk factors were not fully characterized.
How does the extent of coronary artery calcification vary among different types of coronary artery disease in patients undergoing coronary angiography?
Population
2,163 consecutive patients undergoing coronary angiography
Comparison
Patients with acute coronary syndrome vs chronic CAD vs normal subjects or vasospastic angina
Design
Cross-sectional study
Authors
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CAC scoring by cinefluoroscopy may stratify CAD phenotypes; observational data leave open its added value for risk stratification or outcomes.
Cross-Sectional (n=2,163)
No
How does the extent of coronary artery calcification vary among different types of coronary artery disease in patients undergoing coronary angiography?
Absolute Event Rate: 5.48% vs 9.72%
p-value: p=<0.0001
Coronary artery calcification extent varies significantly by the pathological type of ischemic heart disease, being highest in chronic CAD and silent ischemia compared to acute coronary syndromes.
Yamanaka et al. (2002) conducted a cross-sectional in Coronary artery disease (n=2,163). Acute coronary syndrome vs. Chronic coronary artery disease was evaluated on Coronary artery calcification (CAC) score (p=<0.0001). Patients with acute coronary syndrome had a significantly lower coronary artery calcification score (5.48±7.42) compared to those with chronic coronary artery disease (9.72±8.73, p<0.0001).
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