Family cluster study reports transmission and reinfection of human bocavirus 1 in household members, highlighting potential viral latency and reactivation.
Human bocavirus 1 (HBoV1) was detected in a young child hospitalized for pneumonia and subsequently in his twin brother and other family members. The mother's nasopharyngeal samples intermittently showed HBoV1 DNA; the grandmother had HBoV1 reinfection. Findings in this family lead to consideration of HBoV virulence, latency, and reactivation.
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Jula et al. (2013) studied this question.
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