Key result
Acidic and alkaline electrolyzed water reduce foot-and-mouth disease virus titer by ~4 log in vitro.
Why the study?
The potential of acidic and alkaline electrolyzed water as disinfectants against foot-and-mouth disease virus was evaluated due to their possible virucidal effects.
Does electrolyzed water decrease viral titer in foot-and-mouth disease virus in vitro?
Does electrolyzed water decrease viral titer in foot-and-mouth disease virus in vitro?
Acidic and alkaline electrolyzed water demonstrate strong virucidal effects against foot-and-mouth disease virus in vitro.
May support rapid in vitro FMDV disinfection; leaves open in vivo efficacy and field translation.
Acidic electrolyzed water (EW) (pH 2.6-5.8) and alkaline EW (pH 11.2-12.1) were examined as potential disinfectants against foot-and-mouth disease virus (FMDV). Using acidic EW with pH 2.6 and alkaline EW with pH >11.7, the viral titer decreased in vitro by > 4.0 log values, 2 min after the virus was mixed with EW at a 1:10 dilution. The strong virucidal effect of acidic EW (pH 2.6), but not that of alkaline EW (>11.7), seemed to depend on the chlorine level in the solution. Genetic analysis revealed that viral RNA was substantially reduced, especially by alkaline EW.
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Bui et al. (2017) studied Foot-and-mouth disease virus (FMDV) in vitro. Electrolyzed water (acidic and alkaline) vs. Tap water was evaluated on Reduction in viral titer (TCID50) (> 4.0 log values decrease). Acidic electrolyzed water (pH 2.6) and alkaline electrolyzed water (pH >11.7) decreased foot-and-mouth disease virus titer in vitro by >4.0 log values within 2 minutes at a 1:10 dilution.
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