Key result
Chronic Chagas cardiomyopathy features severe chamber dilation, apical LV aneurysms, and diffuse chronic fibrotic myocarditis.
Why the study?
Chagas disease is a zoonotic infectious disease caused by Trypanosoma cruzi with significant morbidity and mortality in endemic regions.
Population
8 million persons infected with Chagas disease in South and Central America and Mexico
Design
Review
Authors
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May inform recognition of Chagas cardiomyopathy pathology; leaves open targeted intervention trials.
Case Report
Provides an overview of the epidemiology and transmission of Chagas disease and its progression to chronic cardiomyopathy.
Aiello et al. (2015) conducted a case report in Chronic Chagas cardiomyopathy. Chronic Chagas cardiomyopathy is characterized by severe dilation of the atrial and ventricular chambers, apical left ventricular aneurysms, and diffuse chronic myocarditis with variable fibrosis.
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