topical use are substantially higher than those achieved by using other forms of administration, and thus there is a good chance of eradicating the infection.If ciprofloxacin or ofloxacin fails, parenteral treatment with ceftazidime or imipenem can be used.12 Until topical ciprofloxacin is commercially available its use will remain restricted in the United Kingdom.Guidelines should be issued for the appropriate use of the drug in chronic otitis media with perforated eardrums, and its introduction for treating chronic otitis externa as well as its use in children should also be considered.
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J. P. Dubey (2000) studied this question.
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