Key result
Integrated RHC hemodynamics identifies extreme PAWP levels as an exceptionally high-risk pulmonary hypertension phenotype.
Why the study?
The risk continuum based on multiple right heart catheterisation measurements in pulmonary hypertension was not fully characterized when modeled together.
Does integrating haemodynamics identify high-risk phenotypes in pulmonary hypertension?
Does integrating haemodynamics identify high-risk phenotypes in pulmonary hypertension?
Integrating multiple right heart catheterisation measurements identifies specific pulmonary artery wedge pressure ranges (>15 mmHg and <12 mmHg) associated with particularly high risk in pulmonary hypertension.
Supports haemodynamic phenotyping for risk stratification in pulmonary hypertension; leaves open whether targeted interventions improve outcomes.
These data illustrate the risk continuum based on multiple right heart catheterisation measurements when modelled together, but also identify pulmonary artery wedge pressure >15 mmHg and <12 mmHg as particularly high riskhttps://bit.ly/3whDEOV
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Oldham et al. (2021) studied this question. Integrating right heart catheterization measurements identifies pulmonary artery wedge pressures >15 mmHg and <12 mmHg as a particularly high-risk pulmonary hypertension phenotype.
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