Vitamin B12 Deficiency: A Cause of Abnormal Movements in Infants

This is the authors' abstract. We don't add key points for this paper.

Experience and Reason| February 01 1997 Vitamin B12 Deficiency: A Cause of Abnormal Movements in Infants Edward Stanley Emery, MD; Edward Stanley Emery, MD Search for other works by this author on: This Site PubMed Google Scholar Alan C. Homans, MD; Alan C. Homans, MD Search for other works by this author on: This Site PubMed Google Scholar Richard B. Colletti, MD Richard B. Colletti, MD Search for other works by this author on: This Site PubMed Google Scholar Reprint requests to (E.S.E.) Department of Neurology, FAHC–UHC Campus, 1 S Prospect St, Burlington, VT 05401. Pediatrics (1997) 99 (2): 255. https://doi.org/10.1542/peds.99.2.255 Article history Received: February 05 1996 Accepted: April 17 1996 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Edward Stanley Emery, Alan C. Homans, Richard B. Colletti; Vitamin B12 Deficiency: A Cause of Abnormal Movements in Infants. Pediatrics February 1997; 99 (2): 255. 10.1542/peds.99.2.255 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search toolbar search search input Search input auto suggest filter your search All PublicationsAll JournalsPediatricsHospital PediatricsPediatrics In ReviewNeoReviewsAAP Grand RoundsAAP NewsAll AAP Sites Search Advanced Search Topics: dyskinesia, vitamin b12 deficiency, glycine, methylmalonic acid Vitamin B12 deficiency is a rare and treatable cause of failure to thrive and delayed development in infants. These infants can exhibit a prominent disorder of movement, a presentation that might be unfamiliar to many physicians. Treatment with vitamin B12 can reverse all of the adverse effects but permanent sequelae may result.1 In developed countries the deficiency usually occurs in infants who are exclusively breastfed, whose mothers have unrecognized pernicious anemia or are vegetarians, causing low stores of vitamin B12 in the infant at birth and inadequate amounts of the vitamin in the breast milk.2 Symptoms and signs of vitamin B12 deficiency appear between the ages of 2 to 12 months and include vomiting, lethargy, failure to thrive, hypotonia, and arrest or regression of developmental skills. Approximately one half of the infants exhibit abnormal movements, variously described as tremors, twitches, chorea, or myoclonus. These movements can be present... You do not currently have access to this content.