Sterically Mediated Two‐Dimensional Architectures in Aggregates of Au Nanoparticles Directed by Phosphorothioate Oligonucleotide‐DNA

Sterically mediated aggregation of gold nanoparticles: 13 nm gold nanoparticles can be arranged in a hexagonal, square, trigonal, or linear manner (see Figure) in two-dimensional (2D) aggregates linked by phosphorothioate oligo-DNA (PS oligo-DNA) of different lengths. The steric effect induced by the parallel orientation of the PS oligo-DNA helix on the particle surface is identified to be of vital importance in controlling the 2D architecture of the particles in the aggregates.